It was 7 p.m. on a Friday, and the streets below in Kendall Square had already emptied out for the weekend when Graham asked Bennett if Moderna would be interested in using the new virus to test the companys accelerated vaccine-making capabilities. It had been 42 days since they designed the vaccine. A few days later, Haller was at her desk for the tech firm where she works in Seattle, taking a break and catching up with her Facebook feed, when she saw a post that Kaiser was searching for volunteers. Hamilton Bennett | Vaccine Congress USA And stand up for science. During dinner, the dings of incoming text messages punctuated his conversation. In the meantime, at Modernaand for all of usthe clock is still ticking. Bringing you daily news at the intersection of biotechnology, politics, patients & the planet. Then, out of nowhere, an Oxford University lab with an experimental vaccine received government permission to jump ahead to Phase 2 based on its prior work, leapfrogging ahead of Moderna. Barouch is no stranger to chasing vaccines. Bancel shook his head. At first, some committee members urged caution. I would come back by 7 a.m. When Bennett heard the good news on a conference call with her colleagues, she said, "I think most of us on the call just sort of shut off and maybe blacked out for a little bit.". Usually partnerships between academic labs and pharma take months to negotiate. Bennett also took pictures outside the state, photographing an ice palace in St. Paul, Minnesota and the World's Columbian Exposition in Chicago, Illinois. Are you sure?, Yeah, her colleague said. Sera from participants immunized on a prime-boost schedule with the mRNA-1273 COVID-19 vaccine were tested for neutralizing activity against several SARS-CoV-2 variants, including variants of concern (VOCs) and variants of interest (VOIs), compared to neutralization of the wild-type SARS-CoV-2 virus (designated as D614G). Bancel would be meeting with President Donald Trump alongside the CEOs of the worlds biggest and most powerful pharmaceutical giants, including Janssen, GlaxoSmithKline, and Sanoficompanies with dozens, in some cases hundreds, of drugs on the market and market caps north of $100 billion. [5] Hamilton Bennett, Senior Director of Vaccine Access and Partnerships at Moderna, works on the company's COVID-19 vaccine from home. Hamilton Bennett (she/her) is the Senior Director of Vaccine Access and Partnerships at Moderna, a company pioneering messenger RNA (mRNA) therapeutics and vaccines. On March 11, Italy closed for business. Bennett, who holds graduate degrees from University of Washington in Environmental Health and Microbiology, as well a certificate in Epidemiology from London School of Hygiene and Tropical Medicine, has over 10 years of research experience and had spent the last four years as a researcher and leader on the company's vaccine portfolio. Haller wasnt fazed. Over several days, Bancel gathered with colleagues to plot out a foolproof shipping strategy. Cost and Value of Biopharmaceuticals. Offers may be subject to change without notice. Previously, it took several minutes for a camera to take a picture, and any movement of the subject being photographed over this time caused the picture to become blurry. Hamilton Bennett Biography | Booking Info for Speaking Engagements The 35-year-old scientist who led Moderna's efforts to create a COVID And if we don't do it, maybe no one else will," Bennett said, while recalling her reasoning at the time. Bennett went back into the software and updated everyones timeline. Her research and development experience and laser-like focus on COVID helped Moderna get its vaccine into early clinical trials within two monthsand receive FDA emergency use authorization by December. But if the risk paid off, the reward would be substantial: It could shave weeks, even months, off the timeline. "I think what we've done is show the world that it's OK to be bold and to stand up and say, 'We can do this,'" said Bennett, adding that it will likely be months before she will be able to fully appreciate her team's hard work. When Haller arrived at the Kaiser building, she pulled into the garage and walked into the clinic, where she learned she would be the very first person in the world to receive the injection. Shouldnt we talk about this? her husband asked when she told him that night that shed signed up. Kaiser needed to find dozens of healthy people who would volunteer as guinea pigs for Modernas Phase 1 safety trial. Early Monday morning, Modernas scientists went to work on a COVID-19 vaccine. An optimized messenger RNA vaccine candidate protects non-human Ultimately, the committee agreed to go for it. biotechnology: biological products (no diagnostic substances), Sr. Project Manager, Clinical Development, Senior Director, Facilities & Engineering | Global Project Lead, Find verified emails and direct dial mobile numbers of contacts on LinkedIn, and sync them with your CRM instantly, Senior Director, Vaccine Access and Partnerships. Read Public Citizen's Letter on the Moderna Vaccine Patent Dispute Others were not convinced that the pandemic would last more than a few months and felt it would be more prudent to wait before moving forward, until there was proof the virus was indeed a threat. If ultimately proven successful in large-scale human trials, mRNA vaccines would herald nothing short of a revolution akin to the advent of the steam engine when it comes to preventing infectious disease. The potential implications of using mRNA as a drug are significant and far-reaching and could meaningfully improve how medicines are discovered, developed and manufactured. He came to Kilbourn City, now called Wisconsin Dells, in 1857, and began his career by purchasing a photographic business in 1865. As soon as she walked into her house, though, she dropped her bag on the floor and fell into a puddle of tears. The group settled in Kilbourn City, today known as Wisconsin Dells, and Henry worked as a carpenter in the town. Health officials warned that it was just the tip of the iceberg. Two days later, on March 2, Bancel flew to the nations capital and got into a car bound for the White House. Hamilton Bennett's email address is h**@modernatx.com. Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants Antimicrobial Resistance. Almost overnight, Bostons streets became eerily quiet as life as we knew it drifted further into a new normal. It was no longer just an interesting experiment on a clinical scale. The site that the NIH had chosen for the trialthe only site it had selectedwas in Seattle. A Shared vision: Henry Hamilton Bennett and William H. Metcalf, A Compelling Vision: H. H. Bennett and the Wisconsin Dells, Items relating to the photographic publishing of H. H. Bennett, https://en.wikipedia.org/w/index.php?title=H._H._Bennett&oldid=1118079413, Pre-Confederation Canadian emigrants to the United States, People of Wisconsin in the American Civil War, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 25 October 2022, at 02:43. The company had also been working for years in conjunction with the National Institutes of Health (NIH) on bringing a new class of vaccines to market. In fact, that data was so encouraging that Bancel was set to announce in a few days time that the company would be doubling down on its vaccine-development program in 2020, with hopes of getting the worlds first mRNA vaccineand what would be Modernas first licensed productonto the market in the next few years. Bennett was no stranger to working at breakneck speed. We need to talk., Within an hour, Barouch had his reply. Sure. He did not disappoint. In the meantime, he continued to innovate in the field of photography by inventing a stop action shutter which allowed him to take photographs of instantaneous events. Sign up for the Good Day BIO Newsletter >. If you're a scraper, please click the link below :-) A major advantage of mRNA is that it is very easy to manufacture these RNA sequences once researchers know the sequence of the viral protein they want to target. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice| Do Not Sell/Share My Personal Information| Ad Choices Bennett received much attention for his advanced techniques, and was commissioned by the Chicago, Milwaukee & St. Paul Railroad to photograph the landscape along the company's track in Wisconsin. Dan Barouch, who heads the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, is something of a prodigy, having run his own research lab since the age of 29. Our tools and initiatives on workforce development, diversity and inclusion are designed to advance a more globally competitive industry. Bennett argued to go for the real vaccine. Up until then, all of the U.S. COVID-19 cases had been imported. Before she knew it, they had halved the time to 60 days. Moderna already had a template to work from, having spent several years designing experimental mRNA vaccines for the Middle East respiratory syndrome coronavirus (MERS-CoV) and the Zika virus. Although the emergence of COVID-19 was first publicly reported in late December 2019, there was still very little known about the viral outbreak. We are going to need a vaccine for this, he wrote. Under the lights on the loading dock, they secured the precious cargo in the truck and closed the door. Being crowned Miss Asia Pageant 1997 effectively launched her career in the fashion and entertainment industry. Hamilton Bennett's research while affiliated with Moderna and other places Overview What is this page? Some said it would divert resources from thriving areas of research and reprioritize other lucrative programs, while betting on a yet unproven vaccine technology. Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, did not anticipate that her team's years of work would soon be thrust into the global spotlight when Moderna became the first American company to jump into the race to a coronavirus vaccine. The only way the world gets back to normal is with broad vaccination.. Less than a year ago, little was known about the mysterious virus that was sickening dozens in Hamilton Bennett's colleagues are Aaron Frank, Abigail Longstaff, Adam Gilmore, Aida Skelic and more. On an industry conference call about emerging infectious diseases on January 29, Bennett listened in as representatives from major pharmaceutical companies hedged and dodged. We will show you what we can do.. By the weekend of January 25, just days after Moderna decided to go full steam ahead, he was convinced the world was going to need a vaccine for this virus. Hamilton Bennett - BIO International Convention | BIO We are here to help! He built himself a portable darkroom, and then towed it, his camera, and other necessary equipment with him across the local countryside taking pictures. International. Moderna scientists had never tried to make a vaccine this quickly before, and there was risk of straining the platform and the team beyond their breaking points. Barouch had worked in the past with Janssen, the pharmaceutical arm of Johnson & Johnson. Human Health. Days later, once she found out shed been selected, several friends tried to dissuade her. This is a great opportunity to go mano a mano with Moderna, he told a reporter from Science magazine. Turn on desktop notifications for breaking stories about interest? Terms & Conditions. She felt as though there was nothing she could do. Hamilton Bennett | 2021 40 Under 40 | Fortune Hamilton Bennett - BIO International Convention | BIO Speaker Hamilton Bennett ASSOCIATE DIRECTOR, VACCINE ACCESS AND PARTNERSHIPS, MODERNA Speaking In 11:00 AM - 12:00 PM Tuesday, June 6 Vaccine manufacturing in Africa: Challenges and opportunities The COVID-19 pandemic highlighted the need for more geographic diversity in the production If you are or someone you know is experiencing a side effect, please reach out to your healthcare professional. Global Markets & Trade. Variant SARS-CoV-2 mRNA vaccines confer broad neutralization - bioRxiv By May, though, Moderna had pulled back into the lead when its Phase 2 trials were approved to start sooner than expected. Learn about our mission, vision, values and priorities, Find out about BIO's programs & initiatives, Meet BIO's Senior Leadership and Board of Directors, Get to know the outstanding people and companies BIO supports, ASSOCIATE DIRECTOR, VACCINE ACCESS AND PARTNERSHIPS, MODERNA, The COVID-19 pandemic highlighted the need for more geographic diversity in the production, 1201 New York Avenue NW, Suite 1300, Washington, DC, 20005 202-962-9200, Vaccine manufacturing in Africa: Challenges and opportunities, BIO Intellectual Property Counsels Committee Conference. 1201 New York Avenue NW, Suite 1300, Washington, DC, 20005 202-962-9200, BIO Intellectual Property Counsels Committee Conference. She needed to sign off on some final risksincluding the fact that the vaccine had not gone through a complete round of animal testingbefore proceeding. It was no longer just an interesting experiment on a clinical scale. Of those that do, not all will make it to Phase 3, and no one knows whichif anywill ultimately prove effective and ostensibly save the world. Photo via AP Photo/Ted S. Warren. But it was his work during the 2016 Zika outbreak that rocketed him to broader fame after he produced an investigational vaccine in a then-unheard-of 180 days. The likely suspects had been ruled out. The company had also been working for years in conjunction with the National Institutes of Health (NIH) on bringing a new class of vaccines to market. Can you get it done?. Bancel forwarded Grahams email to Hamilton Bennett, an energetic and idealistic 35-year-old whod spent the previous three years as program leader on Modernas vaccine portfolio. Find contacts: direct phone number, email address, work experience. But a vaccine based on mRNA had never been approved or authorized by the FDA before. Several days later, on a moonlit Friday night, Bancel wheeled his suitcase into Terminal D at Logan Airport and checked into a red-eye bound for Zurich. At least initially, Bennett didnt know how long it would take Moderna to make its first COVID-19 vaccine. On the flip side, what if it really was needed? Before the meeting officially began, one of the presidents aides introduced Trump to Bancel, explaining that Moderna had the first vaccine ready for trial. However, when the severity of the pandemic became evident, "knowing what mRNA could do, having confidence in our platform, we thought, how do we show the global public health community what mRNA can do in a pandemic?" In addition, because early cameras were unable to accurately capture details of the sky or reflections in water after being adjusted for the light of a typical land photograph, Bennett wove together negatives from multiple photographs of land, sky and water before creating a final print. After the outbreak of the American Civil War, Bennett joined the 12th Wisconsin Infantry Regiment and fought in the Battle of Vicksburg before being severely wounded by the accidental discharge of his own gun. June 5-8, 2023 | Boston, MA People lost their jobs, diagnoses soared, and the body count rose. When it came to Big Pharma, there was less enthusiasm to jump in. See more of The World Libertarians Want on Facebook. She might not be on the frontline, but she at least wanted to be on the battlefield. Across the Charles in Boston, there was one scientist who thought Big Pharma should get on boardand he had a feeling he could make it happen. Contact an All American Speakers Bureau booking agent for more information on Hamilton Bennett speaking fees, availability, speech topics and cost to hire for your next live or virtual event. Hamilton Bennett's HQ phone number is +1 617-714-6500. Barouchs lab had already designed its own COVID-19 virus vaccine as an academic exercise soon after the sequence became available. Join BIO as we champion for bringing new treatments to patients with serious medical conditions and to support policies that promote innovation and improve patient access. After launching successful phase 2 and 3 trials, Moderna reported an efficacy rate of 94.1%. Since its emergence in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has accounted for more than 16 million cases of Coronavirus Disease 2019 (COVID-19) diagnosed worldwide in its first 7 months 3. Title. Hamilton Bennett, Senior Director of Vaccine Access & Partnerships: "Your body gets sort of the software it needs to make its own protein. Less than a year ago, little was known about the mysterious virus that was sickening dozens in China and spreading rapidly unbeknownst to people across the globe. Three days. It can take from 10 to 15 years to develop a new vaccine. China Bennett made all of his own equipment except for the glass lenses in his cameras. After launching successful phase 2 and 3 trials, Moderna reported an efficacy rate of 94.1%. As people across the country saw more and more of Bennett's photographs of the Wisconsin Dells, they began to flock to Kilbourn City to see the rock formations in person. "We believe that our platform is going to make a difference, and we believe that we're uniquely capable of responding to this pandemic. "We'd set our timelines for phase 1, thinking, 'we could possibly start a phase 1 study in April,'" Bennett said. At 8:30 a.m. one morning during the early days of the project, a member of her team delivered the estimated timeline: 120 days. Powered and implemented by Interactive Data Managed Solutions. In the midst of much uncertainty and chaos, Bennett, has emerged as one of the unsung heroes of the pandemic, working feverishly and tirelessly behind the scenes throughout the year to help engineer a vaccine that could potentially save millions of lives. Bancel had been burned by shipping before. Henry Hamilton Bennett | Wisconsin Historical Society Time was of the essence. This marked the first time the virus had spread on our home turf. Next, a pharmacist readied the injection. In the midst of much uncertainty and chaos, Bennett, has emerged as one of the unsung heroes of the pandemic, working feverishly and tirelessly behind the scenes throughout the year to help engineer a vaccine that could potentially save millions of lives. And now, as Moderna awaits potential emergency use authorization by the FDA, Bennett said she is proud of what her team has accomplished. Agriculture & Environment. View Hamilton Bennett's email address: hxxxxxxxxxxxxxxt@modernatx.com & phone: +1-323-xxx-xx74's profile as Senior Director, Vaccine Access and Partnerships at Moderna, located in Malden, Massachusetts. On January 23, Moderna and CEPI went public with the newsbut Bancels attention was focused on the information coming out of Wuhan that day. David L. Ryan/Boston Globe via Getty Images, FILE. On April 6, Inovio, the Pennsylvania company, announced it was approved to start its Phase 1 trial. Scientist Xinhua Yan works in the lab at Moderna in Cambridge, MA, Feb. 28, 2020. Moderna. Hamilton Bennett - Senior Director, Vaccine Access and - LinkedIn Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, did not anticipate that her team's years of work would soon be thrust into the global spotlight when Moderna became the first American company to jump into the race to a coronavirus vaccine. The day CEPI announced it was funding Modernas Phase 1 trial, it also announced it would fund a University of Queensland lab and Pennsylvania-based Inovio Pharmaceuticals. "The world was looking at us because we had started the first study in the U.S. We had done it faster than anyone before had ever done it. That way, Graham mused, if ever there came a day when a new virus emerged that threatened global public health, Moderna and the NIH could know how long it would take them to respond. It almost felt like the world around us was shifting, but for those of us on the program, our entire world was the program," Bennett said. That very day, after Bancel left the White House to head back to Boston, the FDA sent word that they were approving the trial. At 47 years old, his dark hair was thinning but his French accent was as thick as it had been nearly a decade earlier, when he mystified his colleagues by leaving a plum CEO job at a French multinational diagnostics company and moving to Boston to run Modernaat the time a positively tiny Kendall Square biotech that was still operating in stealth mode. Bennett had just entered the estimated 120-day timetable into her project-management software and advised the NIH of the schedule when manufacturing came back and said they could do it even faster. Hamilton Bennett and her team got it done in months. But when the first documented case in the United States was confirmed by the Centers for Disease Control and Prevention on Jan. 20, Bennett's team realized they needed "to move much faster. We will see what they can do, he said. Bennett was widely . "I think when every person in primarily the U.S, but also in our global space has access to a vaccine that's when I think I'm going to be able to breathe, say, 'OK, we've done it,'" she concluded. Unlike more traditional vaccines, which consist of weakened or inactivated forms of a virus, thus stimulating the body's immune response to create antibodies, a vaccine using mRNA sends a set of instructions into cells to teach them to make a protein, which will trigger an immune response inside our bodies to fight off the disease. Bancel, whod spent much of his career at companies that focused on infectious disease, raised his eyebrows. At the time, 35-year-old Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, a small, then-relatively unknown biotech company based in Cambridge, Massachusetts . It was a gamble. At the time, 35-year-old Hamilton Bennett, the senior director of vaccine access and partnerships at Moderna, a small, then-relatively unknown biotech company based in Cambridge, Massachusetts, did not anticipate that her team's years of work would soon be thrust into the global spotlight when Moderna became the first American company to jump into the race to a Copyright 2023 ABC News Internet Ventures. Call us to speak with a booking agent to discuss your event or specific speaker request. Hamilton Bennett - BIO International Convention | BIO Not so long ago, one of Modernas products was left outside of cold storage once it was no longer in the companys hands, and the entire load had to be tossed in the trash. Will it be the first across the finish line? Language links are at the top of the page across from the title. Explore the webinar opportunities for interactive, online learning about emerging issues in biotechnology public policy, scientific progress, and raising capital, plus methods to benefit from BIOs membership services. Hamilton Bennett - BIO International Convention | BIO Since time was of the essence, Moderna decided to do all of the steps simultaneously. Bancel proudly refers to himself as a paranoid optimist. Related Tags: Information on keynote speaking engagements, personal appearances, corporate entertainment and appearance fees for Hamilton Bennett, an inspirational motivational speaker. During the small hours of a cold January morning, Stphane Bancel slipped into the kitchen while his wife and children were still in bed. Bancel knew he needed to reach out to Moderna cofounder Noubar Afeyan, the serial biotech entrepreneur who runs Flagship Pioneering in Cambridge and chairs Modernas board of directors. Contact an All American Speakers Bureau booking agent. Nevertheless, Bennett pressed on in his profession, selling gift shop type items from his studio to attract more customers and continuing as a professional landscape photographer until his death from Bright's disease in 1908. Time was of the essence. On February 7, the chief of technical operations and quality, industry veteran Juan Andres, went to the cafeteria at the Norwood plant for lunch. Since then, new evidence has emerged showing that Moderna did not name NIH scientists as co-inventors in three patent applications covering the composition of the spike protein sequence encoded by mRNA-1273. It can take from 10 to 15 years to develop a new vaccine. At the time, Afeyan was sitting at a marble-topped table at Pammys in Cambridge celebrating his daughters birthday. As the days and nights ground on, the intensity and relentless rhythm of the work started to wear on Bennett. After Bennett created the new shutter, he was able to take clear pictures of moving subjects. One executive mentioned that several biotechs were chasing the vaccine. When they were ready to go, the GPS chips tucked safely inside, there was one last thing to do: The team crowded around the boxes, with big smiles and thumbs up, and snapped a selfie. News of the first U.S. death and the spread of the coronavirus in Seattle were also on Bancels mind, but for slightly different reasons. FORTUNE may receive compensation for some links to products and services on this website. Bennett, who holds graduate degrees from University of Washington in Environmental Health and Microbiology, as well a certificate in Epidemiology from London School of Hygiene and Tropical Medicine, has over 10 years of research experience and had spent the last four years as a researcher and leader on the company's vaccine portfolio. Lets get this started. Much of it wasnt even public and yet here they were, turning their phone screens toward Bancel for him to see. In contrast, Modernas vaccines contain an engineered strand of messenger RNA, which tells the bodys cells to produce a very specific part of a pathogen that will ignite an immune response. Later that evening, he was standing in his kitchen when his phone dinged again. In other words, she was in a position to help, and felt compelled to do so. "We've come a long way in 12 months," Bennett told ABC News in an exclusive interview for "The Shot: Race for the Vaccine," a one-hour special edition of "20/20.". Hamilton Bennett | Speaking Fee | Booking Agent When Bennett heard the good news on a conference call with her colleagues, she said, "I think most of us on the call just sort of shut off and maybe blacked out for a little bit.". My hope for the world is that many of us get to the finish line, so we can stop this thing, Bancel says. "I think when every person in primarily the U.S, but also in our global space has access to a vaccine that's when I think I'm going to be able to breathe, say, 'OK, we've done it,'" she concluded. He originated methods for trimming, printing, washing, and mounting pictures, and devised improvements for his cameras. Trump looked him in the eye and asked, Can I count on you? "We will be kicking off our participation at The World Vaccine Congress in Washington DC with the following sessions: - Hamilton Bennett, our Senior Director of Vaccine Access & Partnerships, will be presenting on 'The role of vaccines in preventing outbreaks, through natural" Traditional vaccines are made from a weakened, dead, or small piece of a pathogena virus or bacteriawhich prompts the body to fight off the invader and builds up immunity for when the real deal comes along. Moderna is continuously monitoring the safety of its products. He was technically on vacation at his home in the south of France, but even on his days off, Bancel didnt sleep much. The popularity of his photographs helped turn the city of Wisconsin Dells, Wisconsin into a tourist destination.

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